New Step by Step Map For ceesdekker
New Step by Step Map For ceesdekker
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Utilizing one-molecule optical and AFM imaging and force-spectroscopy approaches, we search for to unravel the mechanistic facets of the structure and dynamics of chromosomes. Our investigate pursuits incorporate:
You often become involved in discussions about science and religion. You've also written several textbooks on the subject. Don’t you feel that at some point We are going to know every thing Which God’s role will probably be over?
‘It was simply a matter of buying up a reserve on mobile biology and starting to browse. I'd come from a environment of ultra-higher vacuums, cryostats and quantum phenomena, and now I had been Performing at area temperature with molecular biology kits.
Non-equilibrium folding of person DNA molecules recaptured as much as 1000 occasions in a strong state nanopore
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Our analysis ranges from your biophysics of DNA to synthetic cells and past. Remember to have a look beneath on the spectrum of our existing tasks.
‘In the beginning we checked out Organic methods by using a Actual physical see and acted on The idea with the tools we knew. It took a several years right before we started Functioning additional on the ceesdekker.net massive biological problems. I then started to phone it nanobiology, a expression that didn't exist at some time.
2011, very first in vitro measurements of transport throughout an individual biomimetic nuclear pore intricate; growth of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the mechanism of homology recognition in DNA homologous recombination
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Quite neat, but that wasn’t actually wherever my interest lay. I wished to pioneer And that i had the feeling that was no more possible, since the most appealing fundamental insights had previously been uncovered. But my industry had produced quite a few thrilling new instruments to evaluate individual molecules. I decided that I planned to utilize this to biology, to look at it from a physical perspective.’
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Mother nature Physics thanks the nameless reviewers for their contribution to the peer critique of this work.
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2013, managed shaping of Reside bacterial cells into arbitrary styles; and discovery of spontaneous fluctuations within the handedness of histone tetrasomes